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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49820d04a9f9a9e67a8094b852fa9eb468adc23df04f6f48bd912fdf747c650' 
  AND token = 'Ewg8nS6bceAwpyBlW6tp/u9vBsUnytKGGBmWRi9uyuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}