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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87649adddc6f8d976021805aaabe538ecdf3ba037b300080069393a7f43ec6a7' 
  AND token = 'B+vjH2rUy+g2hKdJctAPygxUMlTZRA9H9MEsTLn4ccw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}