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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c395a43ed6a7846b291bf6d3c0a8e04524f4c8611758955d907c345f0303d51' 
  AND token = 'G4N8Dapw0VbLhxbti1fn58Zvw2Uvpl/P1XPGAAeLbcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}