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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74bdde2e5a0906547ac6f03e46f208419f499dbdc5c69064de3d691c0ca95ec5' 
  AND token = 'cuD0h82j8Boq2qAv5/WOc0lj1wSK3y1FHBjaeO2dpCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}