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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41dbd0888b3826e3142c55e50ee4b38c8cb8d16c89aa2551573e5279f325553' 
  AND token = 'NFDeQcQ6dvjQSL7TkWgK9adhh7vUbJ8UkhIRZfvZzak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}