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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e22ac804f34fa68a5ddee784ea462031a59498471e2091f6895174692a1f92c' 
  AND token = 'TFURkJOChqQljSG1FTWipKHBFowl2nuVmPO60psek3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}