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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488ca4b878494ab1e92969743689dc53aab9b90d0349d6c1d1461a5dc5285e0d' 
  AND token = '6lC6UVF6+hwyQo5TEO+pmuLfu4vioTTJu1tLN87WUts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}