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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c064db937dc06e3914754bd304a4aec1a0c2eef5df4ca748f264c195ecc4a1' 
  AND token = '1Y6AcqeaW3RcQ/bXbXnwgNk/BSBdmKRRfxTaX/V6ALo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}