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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4160f75e75d25f5d78cbc3465a823772138a02cca848c865d0e3f8f2de821af8' 
  AND token = 'fri7NHCcRCm8O+tw+1LpOIRL+0YmdUNUsiZ/W3tfagY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}