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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f23bc7d872a204e01f60db296891ad9e3f2ac814212a248a70eaf0b7a45f12' 
  AND token = '6aiYnSWN5jdOnfvwDxVE7lHTQOHIJ0UAWVpaDZLKSXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}