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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e8f650561240531217f063ccfc3089b7e6006be41eb1fb966a72881ad2a072' 
  AND token = '/GWxWnxExI0YyqCfwFV1xL0KQ2c1OMNPIZ9Bvo5dS24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}