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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f157c6c1f49178cf36b7922eea9d791cf3f69402760b1b3cf8e2303c397feb' 
  AND token = 'w3Fzsa+fOKMwLftiwTE6jYGNY+Vg1t5k594jyRk3Y/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}