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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a20e812989589133333ecd2e29c6f47988219bfab8b5f133f8be5da5bd4633bc' 
  AND token = 'YU++TFDAqztUP/wWycryd9fikV2xxRxRPfSyDjX1k6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}