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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c6a441ca78379af0f1a2d3d88744e520a19121fa053e214c4c2b29bd8da87a' 
  AND token = '1960/sYfdkRG0+DMvzmcKlBpslPpMgPEtgzNhHPpBxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}