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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '512fcc56db5102eb377888f11d09239327a49e8099df0867b7a5e35de07483b3' 
  AND token = 't8Lnby47Pm3NAlRcc0CdmZCJCGMi8shRAjRhl5uxaQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}