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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bcfb2dd0be1ea84bdde278bc0f74c9b582b405fb00d3fa05b453fd518dfb3d' 
  AND token = 'JEvEYY+ihQ7I6joo8QnuExI4vACvBaZ4+9ieKbA4gtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}