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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b564fae04712356ceec020b0f04110f30c4d72b828c76f923d890e31904a120d' 
  AND token = 'VMQacm1NQl1ZcZREE1mf4eea6K9xDGBAqt1ySM1ZNnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}