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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2caf7e7cc9ba6c21c98d7e1c148537a74b4d536cffa75e5a7d7fb12fa7b1cc49' 
  AND token = 'pzUE4CPEhmyYkdx/CgkadGbAYUBivtp8UESuqro8TvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}