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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21469851d1c99f01b923d1a8cf4e2204cd1da475df785a6e0862fc5f18abbb5' 
  AND token = 'BIV6jJ7prD5BT4PNbO3Tci9VkYuLi3nVZ1HFiQs8caY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}