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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75134141367728aa598160f94206fe6f3b5f93dcaf01c02aa4747b488af199a9' 
  AND token = '/1+VcCJ0MCSU0s2zfed4RCtUwRk7lodfmWv7YWrCnKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}