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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6ad099cf836a402c110434cfc172d11f4b427b0c75b15d4ff810bf4effcebf' 
  AND token = 'ALxcBx+ndV9bQkfJxr6u+FbIYWhPGQ/UVKLizLj0U5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}