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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b53425b4fde6576f74f202b225f9739e9f76e16e14c33cc790098e1b00eaef' 
  AND token = 'P9HWbq5zrMrIilzYu0r+tAv+bDAwJ4K2dv7A3tC35MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}