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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb0f64a125f801f301c64df91313c3610eb5a46aa09ba99769c941a88871010' 
  AND token = 'ZOnZxkUa0TvWSmxjH7Ljr3acAv/GWKwFrGonXwqZxA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}