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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719b7c64beccdadf939aeab149f08b81ff04422734da1d6d3d4b5db496b9c500' 
  AND token = 'sAm/Fk7AzxMw2Hkr2igS83wG9hXCc2nPsvVa+lqEPA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}