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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451c0110201e73d63d215201bb3c3f2200f8ec6225b7b564c0d4819eea7f5904' 
  AND token = 'y1XNOvbr+bs8yOtFG4PdXSuV29IULRltZJ0qwtVD1eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}