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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b8c6c2f8f9a1a7ff1227bbf5fb9791524715dac522d2f2750b149a8a6e4ebc' 
  AND token = 'w0LwSrUx3R71weKHt40EWafHAlEwNatvNYM5yadsjRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}