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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52db3cd684e1448e583fd4097b22600ea7b62b4a781d5fc5f75e4df372ba4bd' 
  AND token = 'U5kUAbY1TVQnceU1bVUt3y+2NHCt7nwLsXBL9sJJnr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}