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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb0db2b2570e9c9c6dc6619bcc5a6003ab723f6c3bd706db3a28624d86358649' 
  AND token = 'hfYrwdVFuf+VIQW+PzvD0MOWlAk80czuwE6FKWrMjC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}