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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a341d9819f1b6e9a654dead04ce328281cfce438fd076e97b975f2e29f5b232' 
  AND token = 'z4bKGnGkxeDru/XyO+M3UkX1MpC7/sg49y3iY88aZ70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}